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And theres lots of examples in medicine where the theory doesnt quite translate into a therapeutic

Mojsov, S., Weir, G

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ICH Harmonised Guideline E9(R1): Addendum on Estimands and Sensitivity Analysis in Clinical Trials to the Guideline on Statistical Principles for Clinical Trials (2019)

Safety monitoring should account for several important risks: Diabetic retinopathy : Patients with existing retinopathy should be monitored closely, particularly if experiencing rapid improvements in blood glucose levels, as this can temporarily worsen eye complications

But could these medications do morespecifically, improve fertility