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They are not medicines or drugs, have not been evaluated or approved by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease

Vehicle-treated cells were used as controls

Bulk RNA-seq differential expression was performed using DESeq2 Wald tests with the fraction of ribosomal RNA as a covariate and BH correction

Compounding pharmacies faced deadlines of February and March 2025 to cease production

More studies are needed in this area

Obesity has the most severe consequences since it is associated with systemic inflammation, hypertension, and hypercholesterolemia, which represent conditions that increase the risk of developing cardiovascular disease and T2DM