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Initially, we performed an MTS assay by introducing palmitic acid to CAND (Figure

35 tallies = score of 2

Hemoglobin-associated iron depletes GSH reserves, compromising GPX4 functionality in hippocampal cells

We were exploring ways of developing peptides that bind selectively, and we were very successful at that, but then we confronted the problem that our short, 23-residue peptides are not promising therapeutic candidates primarily because they cannot get into cells, Keating says

The mitochondria are surrounded by a delicate lipid bilayer that is highly vulnerable to lipid peroxidationa type of damage caused by unchecked free radicals

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