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This alteration, often caused by increased melanin production, can be permanent and is more common in those with lighter eye colors and older demographics

Epigenetics 9 , 286296 (2013)

The most common side effects in trials were gastrointestinal: nausea, diarrhea, constipation, vomiting, and decreased appetite

doi: 10.1016/j.aquatox.2017.12.017 30 HouWYulinHWenlongYTianTPengFYuqiongDet al

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