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While traditional therapies such as positive airway pressure (PAP) devices are effective in treating OSA and alleviating daytime symptoms, they are often not well tolerated and have limited impact on long-term cardiovascular outcomes

Treatment with either compound 1 (2 100 mg/kg) or 2 (1 100 mg/kg) resulted in significant decreases in both worm and egg burdens of 61% and 57% for 2 and 28% and 31% for 1 , respectively

The undermentioned studies were carried out on a group of diabetic patients [125,126] or cells [127,128]

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