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Glucuronidation (50-60%) - SAFE Primary detoxification pathway in adults Makes acetaminophen water-soluble for excretion INCREASES during pregnancy but cannot compensate for other pathway changes Severely underdeveloped in fetuses/newborns 2

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Matt Segar, MD, a board-certified cardiologist at the Texas Heart Institute, and will be updated as new research and products emerge

However, as the COVID-19 pandemic rapidly evolves and the scientific communitys understanding of the novel coronavirus develops, some of the information may have changed since it was last updated