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For semaglutide specifically, the SmPC advises discontinuation at least 2 months before a planned pregnancy due to its long half-life

Microdosing GLP-1 means using a lower-than-standard dose, but long-term effectiveness hasnt been confirmed in large clinical trials

The Next Chapter in Weight Loss Medicine For years, losing weight felt like an endless cycle of diets, gym memberships, and frustration

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In 2023, Walmart reported that customers who picked up a GLP-1 prescription at its pharmacies were buying only slightly less calories than shoppers with similar behaviors but who did not fill prescriptions for the weight loss drugs at its stores