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Finally, the FLOW trial may shed further light on the potential mechanisms involved on how GLP-1 receptor agonism could alter renal physiology, combined with future mechanistic studies that aim to find proof for the effects of GLP-1 receptor agonists on the renal risk factors/pathophysiological mechanisms related to DKD as summarized in this review

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The fluorescence of resorufin was then measured at an excitation wavelength of 540 nm and an emission wavelength of 590 nm using a photometer (Tecan Infinite M200, Tecan Group Ltd., Mnnedorf, Switzerland)

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