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In the chondrocytes of the iron overload model, the levels of GPX4 and SLC7A11 within the antioxidant system were lower, whereas lipid peroxidation levels, indicated by 4-HNE, were higher, and their mitochondria exhibited characteristics similar to ferroptosis (175)

For the full benefits of NAC, the recommended dosage is 600 mg as often as three times a day

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Cell Death Differ 30:208220 Abutin RM, Chen J, Lung TK, Lloyd JA, Sawyer ST, Harada H (2009) Erythropoietin-induced phosphorylation/degradation of BIM contributes to survival of erythroid cells