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And Pep19, a novel oral peptide that acts as an inverse agonist of the cannabinoid type 1 receptor, showed a 17% visceral fat reduction at the 5mg dose in a 60-day pilot trial, with every subject in the treatment group losing visceral fat

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The FDA's crackdown on compounded GLP-1s (with all grace periods expired by mid-2025) has removed a major unregulated access channel, making formal coverage pathways even more critical

The financial burden creates a significant barrier to treatment adherence, which directly impacts long-term health outcomes