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Bulk-sourced compounds carry risks of contamination, incorrect potency, and unknown identity, with no quality control or regulatory oversight

For patients with severe hypertriglyceridemia (500 mg/dL), dedicated triglyceride-lowering therapy and specialist referral should be considered regardless of tirzepatide use

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DMACA, with its high extinction coefficient at 355 nm and excellent vacuum stability, emerged as an ideal candidate for high spatial resolution dual polarity lipid MALDI-MSI

GPER agonists exert protective effects on endothelial cells by promoting proliferation and migration to facilitate vascular repair, suggesting that GPER has potential protective effects on the cardiovascular health of elderly women [196]