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Gires, O

These results support early genetic screening in children with severe, early-onset obesity and the use of precision therapies like Setmelanotide in genetically confirmed MC4R-pathway disorders

Karan D, Dubey S

L-Carnitine is produced naturally by the body and exists in two biologically active isomers, L-Carnitine and D-Carnitine, which have drastically different effects on the body

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Suggesting that the C-terminal sequence differences between exendin-4 and lixisenatide might impact on these cellular processes, a limited evaluation in our earlier study implied that lixisenatide displays reduced signalling potency and insulinotropism compared to exendin-4 (Jones et al., 2018b)