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Also from Mirati Therapeutics, glesatinib (MGCD265) potently and selectively targets tumors with driver alterations in MET and AXL , and is currently being evaluated in a phase II trial in NSCLC patients exhibiting an activating genetic alteration of MET (NCT02544633)

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Potential Research Applications: Testosterone stimulation and LH activity studies Fertility and reproductive hormone models Testicular function and spermatogenesis research Endocrine system modulation investigations For laboratory research use only

Malberg JE, Duman RS

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