retatrutide side effects phase 2 trial VisualAbstract: reduces body weight by 17.5% in patients with obesity Triple hormone receptor agonist retatrutide

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No food residue, no beverages coating the mucosa

There is no reliable way to predict individual response before initiating treatment, making therapeutic trials necessary

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In addition, patients who experience intolerable side effects are unlikely to benefit from switching to a therapy with similar effects on the gastrointestinal tract