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Obtain baseline serum copper, ceruloplasmin, and liver function tests before initiating therapy

For patients, the practical takeaway is simple

Further understanding of the cellular mechanisms through which microbial metabolites affect BBB physiology would potentially allow microbial-derived metabolites to be exploited for therapeutic protection against BBB breakdown in the context of inflammation, oxidative stress, and age-related diseases

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By following these best practices, patients can receive correct dosing, minimize discomfort, and avoid complications

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