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Survodutide Dosing# In the Phase 2 obesity trial, survodutide was administered as once-weekly subcutaneous injections at doses of 0.6 mg, 2.4 mg, 3.6 mg, and 4.8 mg

In addition, niacin directly inhibits hepatic diacylglycerol O-acyltransferase 2 (DGAT2) the key enzyme in triglyceride synthesis [8], and increases synthesis of apoA1 in the liver, leading to increase in HDL-C concentration [8, 201]

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