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Similar phylogenetic distributions of TrxR-type and transsulfuration-direction Intriguingly, metazoans acquired a novel TrxR enzyme via gene duplication and specialization of Gsr [53, 54] apparently coincident with loss of their Cys Hcy transsulfuration capacity (Fig

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a , Representative images of intestinal NE morphology in wild-type, daf-16(mu86), hif-1(ok2564) or skn-1(zu169) animals grown on cco-1 RNAi bacteria