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Beyond collagen, the research documents antioxidant activity through upregulation of superoxide dismutase, anti-inflammatory effects via suppression of NF-kB signalling, and skin-tightening effects associated with glycosaminoglycan synthesis

Many users report initial benefitssuch as improved digestion, reduced soreness, or less joint tensionwithin 10 to 14 days of consistent use

However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)

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