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However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

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This way the digestive system can slowly learn to digest nutrients until the infants digestive system is ready for the mature milk about 14 days later

These include chromatographic separation methods and mass spectrometric analysis to confirm compound identity, molecular integrity, and purity specifications

after five years, medical review still applies when recurrence risk or active surveillance remains relevant

Lee et al., 2015