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Similarly, PNPLA3 I148M promotes hepatosteatosis through ABHD5-dependent inhibition of PNPLA2 (75), suggesting that small molecules that target the PNPLA3 I148M/ABHD5 interaction could be potential therapeutics for FLD and diabetes

They are also present in parts of the brain involved in appetite, reward, motivation and decision-making

This should aim not only to manage the consequences of stopping treatment but also to alleviate their concerns about them

It is part of the incretin family of hormones, which are released in response to food intake to aid in digestion and glucose metabolism