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It functions as a potent vasodilator, modulates smooth muscle activity in the gastrointestinal tract, and participates in neurotransmission in the central and peripheral nervous systems (Lelievre et al., 2008)

Occasionally, the end of the intestine that has been left in place will need to be brought to the skin's surface to allow waste excretion

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It often starts with weakness and tingling in the legs and can progress to muscle weakness or paralysis

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