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The first successful Phase 3 result, from TRIUMPH-4, showed average weight loss of up to 71.2 pounds in adults with obesity and knee osteoarthritis

& Sowers, J

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Furthermore, studies such as the STEP-HFpEF trial with GLP-1 receptor agonists have shown optimized exercise capacity and reduced heart failure symptoms in patients

Some studies have explored daily GLP1 medications, but they use specially formulated versions designed for daily use not just splitting up a weekly pen

The new pill form changes how GLP-1s are taken but not the underlying reality that outcomes hinge on day-to-day behavior change