is retatrutide glp 1 Diagram showing the mechanism of action of Unapproved weight loss drug retatrutide

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Psychiatry 9, 784

Cognition in mood disorders

Lilly recently reported topline results from the ATTAIN-1 phase-3 trial evaluating orforglipron, a once-daily oral glucagon-like-peptide-1 (GLP-1) receptor agonist for adults with obesity or overweight without diabetes

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Adding the 9mg arm suggests the sponsor believes the 8mg to 12mg range contains the optimal therapeutic dose and wants more granular data to identify it precisely