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GLP-1 Receptor Agonists and NAION: What Clinicians Should Know As GLP-1 receptor agonists (GLP-1 RAs) like semaglutide, liraglutide, and tirzepatide gain prominence in managing diabetes and obesity, its crucial we remain vigilant about rare but significant adverse events

doi:10.1155/2008/682082

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These trials were discontinued because the clinical endpoints did not reach statistical significance when comparing ipamorelin to placebo [5]