This review comprehensively summarizes the role of mitophagy in metabolic diseases, the effects of different types of exercise on mitophagy, and the potential mechanisms of exercise-regulated mitophagy intervention in metabolic diseases, providing new insights for basic and clinical research on exercise intervention for preventing and treating metabolic diseases
*Allele Frequency Aggregator (ALFA) Project It is important to note that not all common genetic variants are disease-causing, especially if they are incredibly common in the human population
37 , 225241.e8 (2015)
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[DOI] [PubMed] [Google Scholar] 120.Dmitrenko D.V., Shnaider N.A., Strotskaya I.G., Kichkaylo A.S., Zobova S.N
Third, adaptive clinical trial designs involving larger patient cohorts and multi-center validation will be crucial to demonstrate efficacy beyond preclinical promise
