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At the cellular level, insulin resistance can be defined as reduced signal transduction along the PI3KAKTmTOR pathway per unit of insulin, resulting in decreased glucose uptake per unit of insulin in adipocytes and skeletal muscle or decreased suppression of hepatic gluconeogenesis

The liver is the bodys primary fat-processing organ

At this dose level, here is what you draw for each concentration: 5mg/ml: 50 units 10mg/ml: 25 units 20mg/ml: 12.5 units 40mg/ml: 6.25 units Most people experience minimal side effects at 2.5mg

doi:10.1038/178064a0