Skin laxity is another concern with weight loss exceeding 15-20% of body weight
Designed to mimic the fat-metabolizing portion of human growth hormone without systemic effects, it showed early promise in animal studies and Phase 1 and 2 human trials
On one side, there are brand-name medications like Wegovy, Ozempic, Mounjaro, and Zepbound manufactured by Novo Nordisk and Eli Lilly, FDA-approved, and widely advertised
They have ingredient lists, but there's no standardization or seals of approval, Jay says
For instance, waist reductions varied between 6.1 and 20.6 cm, directly impacting visceral fat
Who might benefit most from retatrutide for visceral fat reduction