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Michels KA, Wactawski-Wende J, Mills JL, et al

As a 2006 review puts it: There is increasing evidence connecting oxidative stress with a variety of pathological conditions including cancer, cardiovascular diseases, chronic inflammatory disease, post-ischaemic organ injury, diabetes mellitus, xenobiotic/drug toxicity, and rheumatoid arthritis. ( Source 12 ) Vitamin C is a potent antioxidant and is found in generous quantities within the human body

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Studies have shown that GPER activation promotes estrogen-dependent tumor cell proliferation through MAPK, linking GPER expression to tumor progression [50]