The absorbance at 490 nm of each well using a microplate reader (Gen5, Biotek, USA) was recorded to assess the cell viability after the medium was replaced with DMSO
Specifically, curcumin undergoes sulfation mediated by SULT1A1 and SULT1A3 and glucuronidation facilitated by UDP-UGT enzymes (107, 108, 118)
Nanoparticle A15-BLZ-NPs of the FXIIa substrate peptide A15-modified CSF-1R inhibitor sotuletinib (BLZ945) can remodel and activate the anti-tumor immune response by specifically reducing M2-type TAMs by releasing BLZ945 (17)
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