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A comparison of LY2112688 and MC-agonist setmelanotide suggests that the cardiac liabilities of LY2112688 are a molecule-specific limitation, rather than a general feature of MC4R agonism
Key blood pressure findings from clinical research: Average systolic reduction: 7 mmHg 1 Average diastolic reduction: 4 mmHg 1 Increase in normal blood pressure: from 30.2% to 58% of participants 2 Blood pressure reduction appears consistent across different patient subgroups 4 Effects may be partially independent of weight loss 5 Are there any risks associated with taking Mounjaro if you have high blood pressure
Glucagon promotes hepatic fat metabolism, suggesting potential utility in research related to non-alcoholic fatty liver disease (NAFLD)
