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Also, methylation alters the physical accessibility to the nucleic acids by molecular complexes responsible for gene expression and, therefore, may modify or suppress the gene function

If you suspect formulation quality is the issue, ask your provider about switching pharmacies or request a certificate of analysis for your current batch

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Most research protocols use 2.5mg/mL concentration, achieved by reconstituting a 5mg vial with 2mL bacteriostatic water