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Alternative integrin signaling IGF not only binds to IGF-IR/InsR, but also directly binds to other receptors such as integrin, a family of adhesive receptors that promotes cancer stemness and cell survival to adapt to environmental and therapeutic stresses [170, 171]

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While compounding pharmacies can "undoubtedly make better versions of these peptides," UC Davis' Knoepfler says, that doesn't resolve concerns that peptides, especially if taken at the wrong dose, could inadvertently promote cancer growth or trigger a dangerous immune response