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This sexual difference may also influence the ways in which men and women respond to GLP-1-based treatments, which means that future treatments may be formulated taking these differences into account

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The reduction in -cell mass in patients with T2DM can be attributed to -cell apoptosis triggered by multiple factors, including islet amyloid deposition, lipotoxicity, glucotoxicity, and inflammation (You et al., 2022)

These pathway-level markers do not predict response to a specific drug, but they describe the biology a clinician prescribes into, context no subscription tier includes