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One of the human species with major importance, Schistosoma mansoni , is prone to be damaged by NO which disrupts mitochondrial ultrastructure and causes lethal inhibition of aerobic energy metabolism [11,12,13,14]

Always consult with your doctor before altering your medications

For metabolic analysis of cultured cancer cells and tumours, frozen tumour tissue was homogenized in 80% methanol containing 20 mM NEM using a Precellys cold tissue homogenizer (Bertin) at a ratio of 20 mg tissue to 1 ml solvent

TGR was also identified as a multifunctional oxidoreductase with a remarkably wide substrate specificity, capable of directly reducing peroxides, selenium-containing compounds, and several important low-molecular-weight antioxidants, as well as Trx, DTNB, GSSG, and GSH-HED

doi: 10.1371/journal.pntd.0006968 114 BerrimanMHaasBJLoverdePTWilsonRADillonGPCerqueiraGCet al

Planta Med 76(16):18021808