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This deficit correlates with disease activity, suggesting that reduced thymosin alpha-1 may contribute to the immune dysregulation seen in SLE

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Overall, mushroom-derived biomolecules orchestrate complex immune regulation by balancing activation and suppression pathways and show strong potential as food-based immunonutraceuticals and therapeutic adjuncts for inflammatory and autoimmune diseases

It has been proposed that heterodimer formation is restricted to both subunits being from the same class due to dimer interface compatibility interactions

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