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A 2023 observational study published in a peer-reviewed endocrinology journal noted that patients on GLP-1 therapy reported subjective improvements in sleep quality and stress tolerance, metrics often impaired by cortisol dysregulation

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Administration of repeated daily doses of the OC one hour prior to BYETTA administration decreased the mean Cmax of ethinyl estradiol by 15%, but the mean Cmax of levonorgestrel was not significantly changed as compared to when the OC was given alone

The evidence as presented provides the rationale to further investigate this naturally occurring peptide in preclinical and clinical aging studies

Clinics (2018) 73(suppl 1):e473s