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Researchers use AOD 9604 in adipocyte assays, biochemical studies, and preclinical models to investigate lipolysis, fatty acid mobilization, and metabolic pathway regulation without activating the full growth hormone signaling cascade

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Adipocyte specific KO of ABHD5 decreased lipolysis, resulting in reduced FA flux to the liver, and protection against HFD induced hepatic steatosis (149), suggesting that suppressing adipocyte lipolysis could be protective against FLD

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