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(2000) The Journal of Biological Chemistry Mechanistic study demonstrating AOD 9604 directly activates hormone-sensitive lipase and stimulates lipolysis in isolated human adipocytes

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Cardiovascular symptoms : Slow heart rate, low blood pressure, or chest discomfort with cold exposure require prompt evaluation

doi: 10.1007/8904_2016_539 56 WangZRobertsBBuffaJLevisonBZhuWOrgEet al

Patients in whom heart failure (HF) or chronic kidney disease (CKD) is prevalent, should receive a treatment intensification with an SGLT-2 inhibitor with the respective evidence from clinical studies due to the respective data (7072)