My bouts of low potassium were pretty severe in the beginning, but now just uncomfortable
Potential benefits: Lower glucose exposure, less insulin required, sometimes improved variability
6 In a randomized, controlled, crossover study in healthy subjects, consuming 180 mg of curcumin before a carbohydrate-rich meal significantly reduced the incremental area under the curve for plasma glucose over 120 minutes by approximately 36 percent compared with control, without major adverse events
Early studies suggesting benefits of GLP-1 RAs on renal function in patients with reduced eGFR were confirmed by the FLOW trial (Perkovic, NEJM, 2024)
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The honest answer to the question is indirect: semaglutide has been shown to reduce congestion-related symptoms in one specific population studied in a randomized trial, and weight reduction can plausibly ease some forms of dependent lower-limb swelling, but neither of those makes it a treatment for edema
