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Weight loss should also be about how you feel showing up for your life each day: more confident, more energized, and comfortable in your own skin

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The longer you carry excess weight, the more likely you are to accumulate weight-related comorbidities like hypertension, diabetes, sleep apnea, kidney disease, etc.," Harris said

Medications like Wegovy (semaglutide) and Zepbound (tirzepatide) are FDA-approved for weight management

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To further validate the role of the endogenous carnitine shuttle to the observed histone acetylation, we knocked down carnitine O -acetyltransferase (CrAT) and carnitine O -octanoyltransferase (CrOT) (Extended Data Fig