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It has multiple causes , including genetics, hormones and brain chemistry, nutrition, poor sleep, other diseases (like PMOS in my case), and environmental factors, according to the Obesity Medicine Association

J Parenteral Enteral Nutr

At a high level, Ozempic helped define the GLP-1 era

Animal reproduction studies identified increased adverse developmental outcomes from exposure during pregnancy

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The brief duration of action means that endogenous GLP-1 functions as a meal-related signal rather than providing sustained metabolic control