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Semaglutide reduces gallbladder motility, and impaired bile flow can overwhelm the ileum's reabsorption capacity, sending excess bile acids into the colon where they provoke secretory diarrhea 6

doi:10.1111/j.1749-6632.1993.tb19690.x

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Some agentssuch as semaglutidehave stronger supporting data for reducing liver steatosis and improving MASH histology

Originally developed to treat type 2 diabetes, these medications were found to be highly effective for weight loss, leading to their widespread off-label use and, in some cases, FDA approval for weight management

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