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This finding highlights the value of untargeted metabolomics in capturing the expected biochemical signature of MMA and suggests that broader metabolite profiling may provide complementary information alongside conventional biochemical testing and confirmatory diagnostic approaches

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1,5-diCQA markedly reduced the mRNA expression of IL-1 and IL-6 on the ocular surface, encompassing the cornea and conjunctiva, as well as in the exorbital lacrimal gland [72]