Practical measures that may help reduce GI discomfort include: Eating smaller, more frequent meals rather than large portions, to reduce the burden on a stomach that is already emptying more slowly Avoiding high-fat or heavily processed foods , which can exacerbate nausea and slow digestion further Staying well hydrated , particularly if diarrhoea is present, to prevent dehydration Eating slowly and chewing food thoroughly to ease the digestive process Avoiding lying down immediately after eating , which can worsen nausea For constipation specifically, increasing dietary fibre intake (fruits, vegetables, and wholegrains) and maintaining adequate fluid intake are first-line approaches consistent with NHS dietary guidance
On the other side, leucine and glutamine transport by Slc7a8 induces CD47 expression by tumor cells and immune escape in a mouse model of osteosarcoma [166, 167]
Healthcare providers can make Vitamin B12 therapy more effective by watching how patients react to the treatment
Women of childbearing potential should discuss pregnancy planning, as these medications are not recommended during pregnancy and should be discontinued at least 2 months before a planned pregnancy
Pollard JD, Quan T, Li Y, Quan T
doi: 10.3389/fendo.2024.1392306 264 WongJ
