Mitochondrial function declines with age due either to ROS and/or an accumulation of mutations in mitochondrial DNA (151)
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Figure 2 Preclinical Results: Quantification of GSH, MDA, IL-6, TNF-, and IFN- Levels in Healthy Compared to T2DM Subjects For confirmation and demonstration of previous study findings, the levels of the reduced form of GSH, MDA, IL-6, TNF-, and IFN- were compared in healthy and T2DM groups and were measured in the plasma and RBCs isolated from peripheral blood of healthy and T2DM subjects
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g , Analysis of palmitoylation levels of IDH1wt and IDH1mt using various site-directed mutants
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