If you take insulin for diabetes, let your doctor know before you take phentermine, as you may need to adjust your insulin dose
Contraindication: hypothyroidism and history of seizures
Unlike past medications for losing weight, which relied on powerful stimulants with dangerous side effects, GLP-1 agonists seem to have been the first drugs that provided effective long-term weight loss without any risk of harm
Those with obesity-related comorbidities such as obstructive sleep apnea, nonalcoholic fatty liver disease, osteoarthritis, or polycystic ovary syndrome may experience improvements in these conditions as a result of significant weight reduction, though these are not FDA-approved indications for semaglutide
It is also worth noting what the trial did not show
A novel oral formulation of the GLP-1 receptor agonist semaglutide (Rybelsus) was recently approved for the treatment of T2DM