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Leveraging the monoallelic nature of our system, we were able to unequivocally assign peptide restriction for binding core predictions using MHCMotifDecon 1.0 ( We observed that the predicted HLA-DRB1 binding cores from our monoallelic B cell platform matched those obtained from larger muti-allelic MDDC immunopeptidome data sets (Supplementary Fig
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& Rohmer, V
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