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For skin health applications, many experts prefer natural astaxanthin due to its potentially greater efficacy, though more comparative research is needed to definitively establish the differences in outcomes between natural and synthetic forms

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Evidence-based management varies substantially depending on the specific autoimmune disorder, disease severity, organ involvement, and individual patient factors

It is believed to enhance demyelination by secreting various cytokines and chemokines, that attract T-lymphocytes, macrophages, and microglia (Fig