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In addition, the results of an in vitro permeation study on rat skin revealed that drug accumulation within the skin layers was approximately 3 times higher, while the drug flux into the receptor phase of Franz cells was about 6.5 times lower in hydroquinone-loaded SLNs in comparison to the hydroquinone gels which confirmed the reduced systemic absorption and further reduced adverse drug reactions through the encapsulation in SLNs (Wu et al., 2017)

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Steriel gesloten systeem Ontworpen om de integriteit van de onderzoeksoplossing tijdens laboratoriumwerkzaamheden te ondersteunen

For example, a man can go into beast mode during his workouts and still not have his muscles respond like he wants

The importance of such a negative feedback has been well described in the case of HPA axis dysfunctioning following traumatic brain injury (273), and thus contribute to a persistent dyshomeostatic state