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Its prevalence ranges between 5 and 21% 1 , depending on the diagnostic criteria, with higher frequency in women with obesity and specific ethnic groups 2,3

2 By moving to proactive monitorization, the FDA aims to ensure that all promotional content represents a fair balance of risks and benefits, as required by the Federal Food, Drug, and Cosmetic Act

21 In clinical practice, pharmacists can apply this approach by counseling patients on how to monitor for GI AEs and how this correlates with appropriate dose escalation

Treatment typically involves three sessions spaced four to six weeks apart, followed by maintenance sessions every six to twelve months

Turnaround times typically range from 5 to 10 business days

it might be difficult for them to effectively cross the skin due to poor permeability 23